Genetics - Spring 2003

Course: Genetics (BIO 309)

Instructor: John V. Smalley, M.A.

Texts: Principles Of Genetics (7th edition), Tamarin, R. H., 2002.

Genetic Investigations for the Laboratory (3rd edition), Seipelt, R. L., Clark, D. C., and P. M.

Mathis 2002.

Phone: 973-655-7171

Email: smalley@mail.montclair.edu or john_smalley@bloomfield .edu

WWW: http://www.csam.montclair.edu/~smalley

Lecture Meetings: Tuesday & Thursday 8:00 P.M. - 9:45 P.M.

Lab Meetings: Wednesday 6:00 P.M. - 9:00 P.M.

Grading: Lecture Exams (60%), Laboratory/Computer Assignments (20%),

Quizzes (15%), Participation (5%).

Attendance: Required

Tentative Lecture Schedule

Week Topics Reading Assignment

Part I - Transmission Genetics

1-5 Introduction Ch. 1

Cells/Cell Cycle/Cell Division/Chromosomes Ch. 3

Mendelian Genetics Ch. 2

Probability/Hypothesis Testing Ch. 4

Modification Of Mendelian Ratios Ch. 2, 5

Quantitative Genetics I Ch. 18

Linkage & Mapping Ch. 6, 7

Changes In Chromosome Number & Structure Ch. 8, 15

Sex Determination Ch. 5

Week 5 or 6 Exam I

Part II - Molecular Genetics

6-10 DNA - The Genetic Material Ch. 9

DNA Structure Ch. 9

DNA Replication Ch. 9

Transcription Ch. 10

Translation Ch. 11

Gene Regulation Ch. 14, 16

Mutation & Repair Ch. 12

Week 10 or 11 Exam II

Part III - Biotechnology/Population & Evolutionary Genetics

Selected Topics

11-14 Recombinant DNA Technology & Applications Ch. 13

Quantitative Genetics II Ch. 18

Population & Evolutionary Genetics/Evolution Ch. 19-21

Non-Mendelian Genetics Ch. 17

Cancer Genetics/Immunogenetics Ch. 16

Developmental And Behavioral Genetics Ch. 16

Exam III (Date To Be Announced)

Tentative Laboratory Topics

1.) Drosophila Culture Techniques

2.) Setting Up Drosophila Crosses

3.) Mitosis/Meiosis

4.) Genetics Of Ascospore Color In Sordaria

5.) DNA Isolation

6.) Drosophila Eye Pigment Chromatography

7.) UV Induced Mutagenesis In Bacteria

8.) Bacterial Transformation With Plasmid DNA

9.) Restriction Endonuclease Digestion Of Plasmid DNA

10.) DNA Fingerprinting By PCR

11.) Population Genetics I Hardy-Weinberg Simulation

12.) Population Genetics II Determining Genetic Variation

13.) Polygenic Inheritance

14.) Molecular Population Genetics


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Email: smalley@mail.montclair.edu